Small animal PET/CT Unit
The small-animal PET/CT facility allows imaging of mice and rats. Through this imaging method, the biological processes of living organisms are monitored longitudinally, providing a more accurate and quantitative understanding of pathophysiological processes in-situ.
This kind of imaging has the following advantages:
- the whole body is scanned and the obtained data converted in digital form provide quantification of biological processes.
- Less animals can be used in research studies because the same animals can be scanned at different time points (longitudinal studies).
- PET/CT scanners are non-invasive imaging modalities that are already employed in the clinic and hence accurate and reliable preclinical imaging protocols can be translated to the clinical work.
The main goal of PET is the assessment of metabolic response of various organs but at the same time it allows in vivo imaging of different parameters such as cell proliferation, apoptosis, angiogenesis, hypoxia, micro-calcification, inflammation etc. In addition, the utilization of the CT component of the hybrid PET/CT scanner provides gamma rays attenuation correction and accurate anatomic localization of the structures imaged from PET.
In the BRFAA facility, there are experienced researchers who provide assistance in the set-up of experimental imaging studies. The provided services include:
- Hosting animals for small-animal PET/CT scans
- Design and performance of imaging studies
- Processing and data analysis of the scanned animals